MGP Database

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MGP004035

UniProt Annotations

Entry Information
Gene Nametranslocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
Protein EntryTOM70_HUMAN
UniProt IDO94826
SpeciesHuman
Comments
Comment typeDescription
FunctionReceptor that accelerates the import of all mitochondrial precursor proteins. {ECO:0000250}.
Sequence CautionSequence=BAA34439.2; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the Tom70 family. {ECO:0000305}.
SimilarityContains 10 TPR repeats. {ECO:0000255|PROSITE- ProRule:PRU00339}.
Subcellular LocationMitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
SubunitForms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with CAPN8 (By similarity). {ECO:0000250}.
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