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MGP004063

Record overview

MGPD IDMGP004063
Gene ID9956
SpeciesHomo sapiens (Human)
Gene Nameheparan sulfate (glucosamine) 3-O-sulfotransferase 2
Gene Symbol HS3ST2
Synonyms30ST2; 3OST2;
Alternate namesheparan sulfate glucosamine 3-O-sulfotransferase 2; 3-OST-2; h3-OST-2; heparan sulfate 3-O-sulfotransferase 2; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2; heparin-glucosamine 3-O-sulfotransferase;
Chromosome16
Map Location16p12
EC Number2.8.2.29
SummaryHeparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. This gene is expressed predominantly in brain and may play a role in the nervous system. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for HS3ST2

Proteins

heparan sulfate glucosamine 3-O-sulfotransferase 2
Refseq ID:NP_006034
Protein GI:5174463
UniProt ID:Q9Y278
mRNA ID:NM_006043
Length:367
RefSeq Status:
MAYRVLGRAGPPQPRRARRLLFAFTLSLSCTYLCYSFLCCCDDLGRSRLLGAPRCLRGPSAGGQKLLQKSRPCDPSGPTPSEPSAPSAPAAAVPAPRLSG
SNHSGSPKLGTKRLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDRNYGRGLDWYRSLMPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKL
IVVVRNPVTRAISDYTQTLSKKPDIPTFEGLSFRNRTLGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLITDPAGEMGRVQDFLGIKRFITD
KHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQIDPEVIDQLREFYRPYNIKFYETVGQDFRWE
 
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