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MGP004084

UniProt Annotations

Entry Information
Gene Nameglucosamine-6-phosphate deaminase 1
Protein EntryGNPI1_HUMAN
UniProt IDP46926
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P46926-1; Sequence=Displayed; Name=2; IsoId=P46926-2; Sequence=VSP_057011; Note=No experimental confirmation available.;
Catalytic ActivityAlpha-D-glucosamine 6-phosphate + H(2)O = D- fructose 6-phosphate + NH(3).
FunctionSeems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity). {ECO:0000250}.
Sequence CautionSequence=BAA06544.2; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the glucosamine/galactosamine-6-phosphate isomerase family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}.
SubunitHomohexamer. {ECO:0000269|PubMed:12965206}.
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