MGP Database

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MGP004092

UniProt Annotations

Entry Information
Gene Nameinsulin-like 5
Protein EntryINSL5_HUMAN
UniProt IDQ9Y5Q6
SpeciesHuman
Comments
Comment typeDescription
FunctionMay have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor.
SimilarityBelongs to the insulin family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitHeterodimer of a B chain and an A chain linked by two disulfide bonds.
Tissue SpecificityHighly expressed in rectum with lower levels in uterus and ascending and descending colon. {ECO:0000269|PubMed:10458910}.
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