MGP Database

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MGP004119

UniProt Annotations

Entry Information
Gene Nameactin related protein 2/3 complex, subunit 3, 21kDa
Protein EntryARPC3_HUMAN
UniProt IDO15145
SpeciesHuman
Comments
Comment typeDescription
FunctionFunctions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
SimilarityBelongs to the ARPC3 family. {ECO:0000305}.
Subcellular LocationCytoplasm, cytoskeleton. Cell projection.
SubunitComponent of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. {ECO:0000269|PubMed:9230079}.
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