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MGP004151

Record overview

MGPD IDMGP004151
Gene ID10166
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
Gene Symbol SLC25A15
SynonymsHHH; ORC1; ORNT1; D13S327;
Alternate namesmitochondrial ornithine transporter 1; ornithine transporter 1; solute carrier family 25 member 15;
Chromosome13
Map Location13q14
SummaryThis gene is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome.[provided by RefSeq, May 2009]
OrthologsView orthologs and multiple alignments for SLC25A15

Proteins

mitochondrial ornithine transporter 1
Refseq ID:NP_055067
Protein GI:7657585
UniProt ID:Q9Y619
mRNA ID:NM_014252
Length:301
RefSeq Status:
MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVAGLDK
QAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFAS
GRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMNQLEA
Y
 
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