MGP Database

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MGP004234

Ontology/Pathway Information

Entrez Gene ID10419
Gene Nameprotein arginine methyltransferase 5
Gene Symbol PRMT5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0034709 IDA:UniProtKBCmethylosome
GO:0005634 NAS:UniProtKBCnucleus
GO:0003682 IEA:EnsemblFchromatin binding
GO:0001046 ISS:UniProtKBFcore promoter sequence-specific DNA binding
GO:0008469 IBA:GO_CentralFhistone-arginine N-methyltransferase activity
GO:0008168 IDA:MGIFmethyltransferase activity
GO:0035243 IMP:UniProtKBFprotein-arginine omega-N symmetric methyltransferase activity
GO:0043021 IPI:UniProtKBFribonucleoprotein complex binding
GO:0003714 ISS:UniProtKBFtranscription corepressor activity
GO:0008283 TAS:ProtIncPcell proliferation
GO:0032922 ISS:UniProtKBPcircadian regulation of gene expression
GO:0042118 IMP:UniProtKBPendothelial cell activation
GO:0010467 TAS:ReactomePgene expression
GO:0043985 ISS:UniProtKBPhistone H4-R3 methylation
GO:0034660 TAS:ReactomePncRNA metabolic process
GO:0000122 IEA:EnsemblPnegative regulation of transcription from RNA polymerase II promoter
GO:0018216 IMP:UniProtKBPpeptidyl-arginine methylation
GO:0019918 IMP:GOCPpeptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0035246 IDA:MGIPpeptidyl-arginine N-methylation
GO:0007088 TAS:ProtIncPregulation of mitosis
GO:0006355 IBA:GO_CentralPregulation of transcription, DNA-templated
GO:0016070 TAS:ReactomePRNA metabolic process
GO:0000387 IMP:UniProtKBPspliceosomal snRNP assembly
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264165Chromatin modifying enzymes
REACT_264155Chromatin organization
REACT_71Gene Expression
REACT_11052Metabolism of non-coding RNA
REACT_264545RMTs methylate histone arginines
REACT_11066snRNP Assembly
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