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MGP004244

UniProt Annotations

Entry Information
Gene Nameacetyl-CoA acyltransferase 2
Protein EntryTHIM_HUMAN
UniProt IDP42765
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
FunctionAbolishes BNIP3-mediated apoptosis and mitochondrial damage. {ECO:0000269|PubMed:18371312}.
PathwayLipid metabolism; fatty acid metabolism.
SimilarityBelongs to the thiolase family. {ECO:0000305}.
Subcellular LocationMitochondrion {ECO:0000269|PubMed:18371312}. Note=Colocalizes with BNIP3 in the mitochondria.
SubunitHomotetramer. Interacts with BNIP3. {ECO:0000269|PubMed:18371312}.
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