MGP Database

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MGP004267

Ontology/Pathway Information

Entrez Gene ID10498
Gene Namecoactivator-associated arginine methyltransferase 1
Gene Symbol CARM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 ISS:UniProtKBCcytosol
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0008013 TAS:AgBaseFbeta-catenin binding
GO:0008469 IBA:GO_CentralFhistone-arginine N-methyltransferase activity
GO:0042054 IDA:UniProtKBFhistone methyltransferase activity
GO:0035642 ISS:UniProtKBFhistone methyltransferase activity (H3-R17 specific)
GO:0030374 ISS:UniProtKBFligand-dependent nuclear receptor transcription coactivator activity
GO:0070577 ISS:UniProtKBFlysine-acetylated histone binding
GO:0016274 ISS:UniProtKBFprotein-arginine N-methyltransferase activity
GO:0035242 ISS:UniProtKBFprotein-arginine omega-N asymmetric methyltransferase activity
GO:0008276 ISS:UniProtKBFprotein methyltransferase activity
GO:0003713 ISS:UniProtKBFtranscription coactivator activity
GO:0044212 ISS:UniProtKBFtranscription regulatory region DNA binding
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0060350 IEA:EnsemblPendochondral bone morphogenesis
GO:0034971 ISS:UniProtKBPhistone H3-R17 methylation
GO:0034970 IMP:UniProtKBPhistone H3-R2 methylation
GO:0016571 IDA:UniProtKBPhistone methylation
GO:0030520 IEA:EnsemblPintracellular estrogen receptor signaling pathway
GO:0032091 IEA:EnsemblPnegative regulation of protein binding
GO:0009405 IEA:InterProPpathogenesis
GO:0019919 IBA:GO_CentralPpeptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0008284 IEA:EnsemblPpositive regulation of cell proliferation
GO:0045600 ISS:UniProtKBPpositive regulation of fat cell differentiation
GO:0003420 IEA:EnsemblPregulation of growth plate cartilage chondrocyte proliferation
GO:0033146 ISS:UniProtKBPregulation of intracellular estrogen receptor signaling pathway
GO:0006355 ISS:UniProtKBPregulation of transcription, DNA-templated
GO:0051591 IEA:EnsemblPresponse to cAMP
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147904Activation of gene expression by SREBF (SREBP)
REACT_111118BMAL1:CLOCK,NPAS2 activates circadian gene expression
REACT_264165Chromatin modifying enzymes
REACT_264155Chromatin organization
REACT_24941Circadian Clock
REACT_111045Developmental Biology
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_71Gene Expression
REACT_12627Generic Transcription Pathway
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_264351Mitochondrial biogenesis
REACT_264135Organelle biogenesis and maintenance
REACT_268444Orphan transporters
REACT_116145PPARA activates gene expression
REACT_147797Regulation of cholesterol biosynthesis by SREBP (SREBF)
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
REACT_118789REV-ERBA represses gene expression
REACT_264545RMTs methylate histone arginines
REACT_118659RORA activates circadian gene expression
REACT_264212Transcriptional activation of mitochondrial biogenesis
REACT_27161Transcriptional regulation of white adipocyte differentiation
REACT_15518Transmembrane transport of small molecules
REACT_118713YAP1- and WWTR1 (TAZ)-stimulated gene expression
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