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MGP004282

Record overview

MGPD IDMGP004282
Gene ID10554
SpeciesHomo sapiens (Human)
Gene Name1-acylglycerol-3-phosphate O-acyltransferase 1
Gene Symbol AGPAT1
SynonymsG15; LPAATA; 1-AGPAT1; LPAAT-alpha;
Alternate names1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; 1-AGP acyltransferase 1; 1-AGPAT 1; 1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase); 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha); lysophosphatidic acid acyltransferase alpha; lysophospholipid acyltransferase;
Chromosome6
Map Location6p21.3
EC Number2.3.1.51
SummaryThis gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for AGPAT1

Proteins

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
Refseq ID:NP_116130
Protein GI:15100175
UniProt ID:Q99943
mRNA ID:NM_032741
Length:283
RefSeq Status:
MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVV
VSNHQSSLDLLGMMEVLPGRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQ
AQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
 
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
Refseq ID:NP_006402
Protein GI:5453718
UniProt ID:Q99943
mRNA ID:NM_006411
Length:283
RefSeq Status:
Protein sequence is identical to GI:15100175 (mRNA isoform)
 
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