MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP004373

UniProt Annotations

Entry Information
Gene Namealdehyde dehydrogenase 1 family, member L1
Protein EntryAL1L1_HUMAN
UniProt IDO75891
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=4; Name=1; IsoId=O75891-1; Sequence=Displayed; Name=2; IsoId=O75891-2; Sequence=VSP_045569; Note=No experimental confirmation available.; Name=3; IsoId=O75891-3; Sequence=VSP_047260; Name=4; IsoId=O75891-4; Sequence=VSP_057429, VSP_057430; Note=No experimental confirmation available.;
Catalytic Activity10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
SimilarityContains 1 acyl carrier domain. {ECO:0000255|PROSITE- ProRule:PRU00258}.
SimilarityIn the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. {ECO:0000305}.
SimilarityIn the N-terminal section; belongs to the GART family. {ECO:0000305}.
Subcellular LocationCytoplasm.
Tissue SpecificityHighly expressed in liver, pancreas and kidney. {ECO:0000269|PubMed:20498374}.
  logo