MGP Database

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MGP004391

Ontology/Pathway Information

Entrez Gene ID10892
Gene NameMALT1 paracaspase
Gene Symbol MALT1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0032449 NAS:UniProtKBCCBM complex
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005730 IDA:HPACnucleolus
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IEA:UniProtKB-SubCellCperinuclear region of cytoplasm
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043234 IDA:UniProtKBCprotein complex
GO:0004197 NAS:UniProtKBFcysteine-type endopeptidase activity
GO:0008233 IDA:BHF-UCLFpeptidase activity
GO:0043621 IPI:UniProtKBFprotein self-association
GO:0004871 IMP:UniProtKBFsignal transducer activity
GO:0004842 IDA:UniProtKBFubiquitin-protein transferase activity
GO:0007250 IMP:UniProtKBPactivation of NF-kappaB-inducing kinase activity
GO:0001923 IEA:EnsemblPB-1 B cell differentiation
GO:0006952 NAS:UniProtKBPdefense response
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0043066 NAS:UniProtKBPnegative regulation of apoptotic process
GO:0051168 IDA:UniProtKBPnuclear export
GO:0043123 IMP:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032743 IMP:UniProtKBPpositive regulation of interleukin-2 production
GO:0051092 IMP:BHF-UCLPpositive regulation of NF-kappaB transcription factor activity
GO:0031398 NAS:BHF-UCLPpositive regulation of protein ubiquitination
GO:0050870 IC:UniProtKBPpositive regulation of T cell activation
GO:0002726 IMP:UniProtKBPpositive regulation of T cell cytokine production
GO:0051259 IDA:UniProtKBPprotein oligomerization
GO:0016567 IDA:GOCPprotein ubiquitination
GO:0006508 IDA:BHF-UCLPproteolysis
GO:0042981 IDA:MGIPregulation of apoptotic process
GO:0050856 IEA:EnsemblPregulation of T cell receptor signaling pathway
GO:0009620 IEA:EnsemblPresponse to fungus
GO:0002237 IEA:EnsemblPresponse to molecule of bacterial origin
GO:0042098 IEA:EnsemblPT cell proliferation
GO:0050852 IDA:UniProtKBPT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118656Activation of NF-kappaB in B cells
REACT_75774Adaptive Immune System
REACT_118638Downstream signaling events of B Cell Receptor (BCR)
REACT_12555Downstream TCR signaling
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_163994FCERI mediated NF-kB activation
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_12526TCR signaling
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