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MGP004548

Record overview

MGPD IDMGP004548
Gene ID22934
SpeciesHomo sapiens (Human)
Gene Nameribose 5-phosphate isomerase A
Gene Symbol RPIA
SynonymsRPI;
Alternate namesribose-5-phosphate isomerase; phosphoriboisomerase; ribose 5-phosphate epimerase;
Chromosome2
Map Location2p11.2
EC Number5.3.1.6
SummaryThe protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18. [provided by RefSeq, Mar 2010]
OrthologsView orthologs and multiple alignments for RPIA

Proteins

ribose-5-phosphate isomerase
Refseq ID:NP_653164
Protein GI:94536842
UniProt ID:P49247
mRNA ID:NM_144563
Length:311
RefSeq Status:
MQRPGPFSTLYGRVLAPLPGRAGGAASGGGGNSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPAPSTMSKAEEAKKLAGRAAVENHVRNNQVL
GIGSGSTIVHAVQRIAERVKQENLNLVCIPTSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLTQEKIVAGYASRFIVIADFRK
DSKNLGDQWHKGIPIEVIPMAYVPVSRAVSQKFGGVVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAIKMIPGVVDTGLFINMAERVYFGMQD
GSVNMREKPFC
 
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