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MGP004575

Record overview

MGPD IDMGP004575
Gene ID23057
SpeciesHomo sapiens (Human)
Gene Namenicotinamide nucleotide adenylyltransferase 2
Gene Symbol NMNAT2
SynonymsPNAT2; C1orf15;
Alternate namesnicotinamide mononucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NaMN adenylyltransferase 2; nicotinate-nucleotide adenylyltransferase 2; pyridine nucleotide adenylyltransferase 2;
Chromosome1
Map Location1q25
EC Number2.7.7.1
SummaryThis gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for NMNAT2

Proteins

nicotinamide mononucleotide adenylyltransferase 2 isoform 1
Refseq ID:NP_055854
Protein GI:24307989
UniProt ID:Q9BZQ4
mRNA ID:NM_015039
Length:307
RefSeq Status:
MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLE
HHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCG
SDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ
LYINASG
 
nicotinamide mononucleotide adenylyltransferase 2 isoform 2
Refseq ID:NP_733820
Protein GI:25141325
UniProt ID:Q9BZQ4
mRNA ID:NM_170706
Length:302
RefSeq Status:
MEIQELEEIQACQGLWEVFVTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDL
MKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLE
SFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINA
SG
 
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