MGP Database

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MGP004592

UniProt Annotations

Entry Information
Gene Namecollagen beta(1-O)galactosyltransferase 2
Protein Entry
UniProt ID
SpeciesHuman
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=33.5 uM for UDP-galactose {ECO:0000269|PubMed:19075007};
Catalytic ActivityUDP-alpha-D-galactose + 5-hydroxy-L-lysine- [procollagen] = UDP + 5-(D-galactosyloxy)-L-lysine-[procollagen]. {ECO:0000269|PubMed:19075007}.
CautionHas no glucosyltransferase activity. {ECO:0000305}.
FunctionHas a beta-galactosyltransferase activity; transfers beta-galactose to hydroxylysine residues on collagen. {ECO:0000269|PubMed:19075007}.
Sequence CautionSequence=BAA25510.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
SimilarityBelongs to the glycosyltransferase 25 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
Tissue SpecificityExpressed in brain and skeletal muscle. {ECO:0000269|PubMed:19075007}.
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