MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP004601

Record overview

MGPD IDMGP004601
Gene ID23171
SpeciesHomo sapiens (Human)
Gene Nameglycerol-3-phosphate dehydrogenase 1-like
Gene Symbol GPD1L
SynonymsGPD1-L;
Alternate namesglycerol-3-phosphate dehydrogenase 1-like protein;
Chromosome3
Map Location3p22.3
EC Number1.1.1.8;
SummaryThe protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010]
OrthologsView orthologs and multiple alignments for GPD1L

Proteins

glycerol-3-phosphate dehydrogenase 1-like protein
Refseq ID:NP_055956
Protein GI:24307999
UniProt ID:Q8N335
mRNA ID:NM_015141
Length:351
RefSeq Status:
MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFI
HRICDEITGRVPKKALGITLIKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQTPNFRITVVDDADTVE
LCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ
GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT
 
  logo