MGP Database

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MGP004604

UniProt Annotations

Entry Information
Gene Nameral guanine nucleotide dissociation stimulator-like 1
Protein EntryRGL1_HUMAN
UniProt IDQ9NZL6
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=A; IsoId=Q9NZL6-1; Sequence=Displayed; Name=B; IsoId=Q9NZL6-2; Sequence=VSP_001824;
FunctionProbable guanine nucleotide exchange factor.
Sequence CautionSequence=BAA76803.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityContains 1 N-terminal Ras-GEF domain. {ECO:0000255|PROSITE-ProRule:PRU00135}.
SimilarityContains 1 Ras-associating domain. {ECO:0000255|PROSITE-ProRule:PRU00166}.
SimilarityContains 1 Ras-GEF domain. {ECO:0000255|PROSITE- ProRule:PRU00168}.
SubunitInteracts with Ras. {ECO:0000250}.
Tissue SpecificityExpressed in a wide variety of tissues with strong expression being seen in the heart, brain, kidney, spleen and testis.
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