MGP Database

MGP004683

UniProt Annotations

Entry Information
Gene Nametranslocation associated membrane protein 1
Protein EntryTRAM1_HUMAN
UniProt IDQ15629
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q15629-1; Sequence=Displayed; Name=2; IsoId=Q15629-2; Sequence=VSP_056213; Note=No experimental confirmation available.;
FunctionStimulatory or required for the translocation of secretory proteins across the ER membrane.
InteractionP51572:BCAP31; NbExp=5; IntAct=EBI-1788852, EBI-77683;
SimilarityBelongs to the TRAM family. {ECO:0000305}.
SimilarityContains 1 TLC (TRAM/LAG1/CLN8) domain. {ECO:0000255|PROSITE-ProRule:PRU00205}.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein.
SubunitInteracts with human cytomegalovirus/HHV-5 protein US2. {ECO:0000269|PubMed:19121997}.
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