MGP Database

MGP004716

UniProt Annotations

Entry Information
Gene Nameopsin 3
Protein EntryOPN3_HUMAN
UniProt IDQ9H1Y3
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; Synonyms=1-4b-5-6; IsoId=Q9H1Y3-1; Sequence=Displayed; Name=2; Synonyms=1-2-5-6; IsoId=Q9H1Y3-2; Sequence=VSP_010209;
FunctionMay play a role in encephalic photoreception.
SimilarityBelongs to the G-protein coupled receptor 1 family. Opsin subfamily. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationMembrane; Multi-pass membrane protein.
Tissue SpecificityStrongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
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