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MGP004732

UniProt Annotations

Entry Information
Gene Nametripartite motif containing 29
Protein EntryTRI29_HUMAN
UniProt IDQ14134
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=Alpha; IsoId=Q14134-1; Sequence=Displayed; Name=Beta; IsoId=Q14134-2; Sequence=VSP_011999; Note=No experimental confirmation available.;
FunctionIt is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.
InteractionO15169:AXIN1; NbExp=2; IntAct=EBI-702370, EBI-710484; O14641:DVL2; NbExp=5; IntAct=EBI-702370, EBI-740850; Q96CN9:GCC1; NbExp=2; IntAct=EBI-702370, EBI-746252; P49841:GSK3B; NbExp=2; IntAct=EBI-702370, EBI-373586;
PtmConstitutively phosphorylated by PKC on serine/threonine in A431 cells. {ECO:0000269|PubMed:16964243, ECO:0000269|PubMed:18669648, ECO:0000269|PubMed:20068231, ECO:0000269|PubMed:8647648}.
SimilarityContains 1 B box-type zinc finger. {ECO:0000255|PROSITE-ProRule:PRU00024}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:7644499}. Note=Colocalizes with intermediate filaments.
SubunitInteracts with VIM and HINT1. {ECO:0000269|PubMed:7644499}.
Tissue SpecificityExpressed in placenta, prostate and thymus. {ECO:0000269|PubMed:11331580}.
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