MGP Database

MGP004733

UniProt Annotations

Entry Information
Gene Namesolute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
Protein EntryXCT_HUMAN
UniProt IDQ9UPY5
SpeciesHuman
Comments
Comment typeDescription
FunctionSodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. {ECO:0000269|PubMed:15151999}.
InteractionP16070:CD44; NbExp=4; IntAct=EBI-3843348, EBI-490245;
SimilarityBelongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000269|PubMed:15151999}; Multi-pass membrane protein {ECO:0000269|PubMed:15151999}.
SubunitDisulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc. {ECO:0000250}.
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