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MGP004742

UniProt Annotations

Entry Information
Gene Namephosphatidylserine decarboxylase
Protein EntryPISD_HUMAN
UniProt IDQ9UG56
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9UG56-3; Sequence=Displayed; Name=2; IsoId=Q9UG56-2; Sequence=VSP_007540; Note=No experimental confirmation available.;
Catalytic ActivityPhosphatidyl-L-serine = phosphatidylethanolamine + CO(2).
CofactorName=pyruvate; Xref=ChEBI:CHEBI:15361; Evidence={ECO:0000250}; Note=Binds 1 pyruvoyl group covalently per subunit. {ECO:0000250};
PathwayPhospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.
Sequence CautionSequence=CAB43678.2; Type=Erroneous translation; Evidence={ECO:0000305};
SimilarityBelongs to the phosphatidylserine decarboxylase family. {ECO:0000305}.
Subcellular LocationMitochondrion {ECO:0000250}.
SubunitHeterodimer. {ECO:0000250}.
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