MGP Database

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MGP004759

Record overview

MGPD IDMGP004759
Gene ID25802
SpeciesHomo sapiens (Human)
Gene Nameleiomodin 1 (smooth muscle)
Gene Symbol LMOD1
Synonyms1D; D1; 64kD; SMLMOD; SM-LMOD;
Alternate namesleiomodin-1; 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; leimodin 1 (smooth muscle); leiomodin, muscle form; smooth muscle leiomodin; thyroid and eye muscle autoantigen D1 (64kD); thyroid-associated ophthalmopathy autoantigen;
Chromosome1
Map Location1q32
Summary The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for LMOD1

Proteins

leiomodin-1
Refseq ID:NP_036266
Protein GI:112380630
UniProt ID:P29536
mRNA ID:NM_012134
Length:600
RefSeq Status:
MSRVAKYRRQVSEDPDIDSLLETLSPEEMEELEKELDVVDPDGSVPVGLRQRNQTEKQSTGVYNREAMLNFCEKETKKLMQREMSMDESKQVETKTDAKN
GEERGRDASKKALGPRRDSDLGKEPKRGGLKKSFSRDRDEAGGKSGEKPKEEKIIRGIDKGRVRAAVDKKEAGKDGRGEERAVATKKEEEKKGSDRNTGL
SRDKDKKREEMKEVAKKEDDEKVKGERRNTDTRKEGEKMKRAGGNTDMKKEDEKVKRGTGNTDTKKDDEKVKKNEPLHEKEAKDDSKTKTPEKQTPSGPT
KPSEGPAKVEEEAAPSIFDEPLERVKNNDPEMTEVNVNNSDCITNEILVRFTEALEFNTVVKLFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHIT
GKGILAIFRALLQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTNLLSRNMDKQRQKRLQEQRQAQEAKGEKKDLLEVPK
AGAVAKGSPKPSPQPSPKPSPKNSPKKGGAPAAPPPPPPPLAPPLIMENLKNSLSPATQRKMGDKVLPAQEKNSRDQLLAAIRSSNLKQLKKVEVPKLLQ
 
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