MGP Database

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MGP004774

UniProt Annotations

Entry Information
Gene Namemitochondrial pyruvate carrier 2
Protein EntryMPC2_HUMAN
UniProt IDO95563
SpeciesHuman
Comments
Comment typeDescription
FunctionMediates the uptake of pyruvate into mitochondria. {ECO:0000269|PubMed:22628558}.
SimilarityBelongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. {ECO:0000305}.
Subcellular LocationMitochondrion inner membrane {ECO:0000269|PubMed:22628558}; Multi-pass membrane protein {ECO:0000269|PubMed:22628558}.
SubunitThe functional 150 kDa pyruvate import complex is a heteromer of MPC1 and MPC2. {ECO:0000250|UniProtKB:Q9D023}.
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