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MGP004898

Record overview

MGPD IDMGP004898
Gene ID27010
SpeciesHomo sapiens (Human)
Gene Namethiamin pyrophosphokinase 1
Gene Symbol TPK1
SynonymsPP20; HTPK1; THMD5;
Alternate namesthiamin pyrophosphokinase 1; placental protein 20; thiamine diphosphokinase; thiamine kinase;
Chromosome7
Map Location7q34-q35
EC Number2.7.6.2
SummaryThis gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for TPK1

Proteins

thiamin pyrophosphokinase 1 isoform a
Refseq ID:NP_071890
Protein GI:21362110
UniProt ID:Q9H3S4
mRNA ID:NM_022445
Length:243
RefSeq Status:
MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTD
FTKCLKMLQKKIEEKDLKVDVIVTLGGLAGRFDQIMASVNTLFQATHITPFPIIIIQEESLIYLLQPGKHRLHVDTGMEGDWCGLIPVGQPCMQVTTTGL
KWNLTNDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS
 
thiamin pyrophosphokinase 1 isoform b
Refseq ID:NP_001035947
Protein GI:110227857
UniProt ID:Q9H3S4
mRNA ID:NM_001042482
Length:194
RefSeq Status:
MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGANRLYDITEGERESFLPEFINGDFDSIRPEVREYYATKGCELISTPDQDHTD
FTKCLKMLQKKIEEKDLKGKHRLHVDTGMEGDWCGLIPVGQPCMQVTTTGLKWNLTNDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS
 
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