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MGP004908

Record overview

MGPD IDMGP004908
Gene ID27063
SpeciesHomo sapiens (Human)
Gene Nameankyrin repeat domain 1 (cardiac muscle)
Gene Symbol ANKRD1
SynonymsALRP; CARP; C-193; CVARP; MCARP; bA320F15.2;
Alternate namesankyrin repeat domain-containing protein 1; cardiac ankyrin repeat protein; cytokine-inducible gene C-193 protein; cytokine-inducible nuclear protein; liver ankyrin repeat domain 1;
Chromosome10
Map Location10q23.31
SummaryThe protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ANKRD1

Proteins

ankyrin repeat domain-containing protein 1
Refseq ID:NP_055206
Protein GI:38327522
UniProt ID:Q15327
mRNA ID:NM_014391
Length:319
RefSeq Status:
MMVLKVEELVTGKKNGNGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYR
KTKVPVVKEPEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLD
VLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHWQNGTK
AIFDSLRENSYKTSRIATF
 
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