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MGP004940

Record overview

MGPD IDMGP004940
Gene ID27232
SpeciesHomo sapiens (Human)
Gene Nameglycine N-methyltransferase
Gene Symbol GNMT
Alternate namesglycine N-methyltransferase; HEL-S-182mP; epididymis secretory sperm binding protein Li 182mP;
Chromosome6
Map Location6p12
EC Number2.1.1.20;
SummaryThe protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). [provided by RefSeq, Oct 2008]
OrthologsView orthologs and multiple alignments for GNMT

Proteins

glycine N-methyltransferase
Refseq ID:NP_061833
Protein GI:9506741
UniProt ID:Q14749
mRNA ID:NM_018960
Length:295
RefSeq Status:
MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERW
NRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSD
LTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD
 
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