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MGP004990

Record overview

MGPD IDMGP004990
Gene ID29085
SpeciesHomo sapiens (Human)
Gene Namephosphohistidine phosphatase 1
Gene Symbol PHPT1
SynonymsPHP14; CGI-202; HSPC141; HEL-S-132P;
Alternate names14 kDa phosphohistidine phosphatase; epididymis secretory sperm binding protein Li 132P; protein janus-A homolog; sex-regulated protein janus-a;
Chromosome9
Map Location9q34.3
EC Number3.1.3.-
SummaryThis gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
OrthologsView orthologs and multiple alignments for PHPT1

Proteins

14 kDa phosphohistidine phosphatase isoform 2
Refseq ID:NP_001129333
Protein GI:209529723
UniProt ID:Q9NRX4
mRNA ID:NM_001135861
Length:124
RefSeq Status:
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMMRPTC
VPLGASGPRIHHQGLWSCPARHFN
 
14 kDa phosphohistidine phosphatase isoform 3
Refseq ID:NP_054891
Protein GI:24475861
UniProt ID:Q9NRX4
mRNA ID:NM_014172
Length:125
RefSeq Status:
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYGPA
QHAISTEKIKAKYPDYEVTWANDGY
 
14 kDa phosphohistidine phosphatase isoform 4
Refseq ID:NP_001274271
Protein GI:565324201
UniProt ID:
mRNA ID:NM_001287342
Length:127
RefSeq Status:
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHGEADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMAYG
PAQHAISTEKIKAKYPDYEVTWANDGY
 
14 kDa phosphohistidine phosphatase isoform 5
Refseq ID:NP_001274272
Protein GI:565324185
UniProt ID:
mRNA ID:NM_001287343
Length:125
RefSeq Status:
MAVADLALIPDVDIDSDGVFKYVLIRVHSAPRSGAPAAESKEIVRGYKWAEYHADIYDKVSGDMQKQGCDCECLGGGRISHQSQDKKIHVYGYSMQMRPT
CVPLGASGPRIHHQGLWSCPARHFN
 
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