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MGP005018

Record overview

MGPD IDMGP005018
Gene ID29920
SpeciesHomo sapiens (Human)
Gene Namepyrroline-5-carboxylate reductase family, member 2
Gene Symbol PYCR2
SynonymsP5CR2;
Alternate namespyrroline-5-carboxylate reductase 2; P5C reductase 2; pyrroline 5-carboxylate reductase isoform;
Chromosome1
Map Location1q42.12
EC Number1.5.1.2;
SummaryThis gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
OrthologsView orthologs and multiple alignments for PYCR2

Proteins

pyrroline-5-carboxylate reductase 2 isoform 1
Refseq ID:NP_037460
Protein GI:21361454
UniProt ID:Q96C36
mRNA ID:NM_013328
Length:320
RefSeq Status:
MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVT
ISSVEKKLMAFQPAPKVIRCMTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAFMALDALADGGVKMGLPRR
LAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTL
TPSSPGKLLTRSLALGGKKD
 
pyrroline-5-carboxylate reductase 2 isoform 2
Refseq ID:NP_001258610
Protein GI:410991931
UniProt ID:Q96C36
mRNA ID:NM_001271681
Length:246
RefSeq Status:
MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVT
ISSVEKAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQ
EKISPAALKKTLLDRVKLESPTVSTLTPSSPGKLLTRSLALGGKKD
 
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