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MGP005020

Record overview

MGPD IDMGP005020
Gene ID29925
SpeciesHomo sapiens (Human)
Gene NameGDP-mannose pyrophosphorylase B
Gene Symbol GMPPB
SynonymsMDDGA14; MDDGB14; MDDGC14;
Alternate namesmannose-1-phosphate guanyltransferase beta; GTP-mannose-1-phosphate guanylyltransferase beta;
Chromosome3
Map Location3p21.31
EC Number2.7.7.13
SummaryThis gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2009]
OrthologsView orthologs and multiple alignments for GMPPB

Proteins

mannose-1-phosphate guanyltransferase beta isoform 1
Refseq ID:NP_037466
Protein GI:11761619
UniProt ID:Q9Y5P6
mRNA ID:NM_013334
Length:387
RefSeq Status:
MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSET
ADPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPAVLRRIQLQPTSIEKEVFPI
MAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKQPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDARIRSH
SWLESCIVGWRCRVGQWVSLWAGLGGERGGECACLPDKAYPLLEVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM
 
mannose-1-phosphate guanyltransferase beta isoform 2
Refseq ID:NP_068806
Protein GI:11761621
UniProt ID:Q9Y5P6
mRNA ID:NM_021971
Length:360
RefSeq Status:
MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSET
ADPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPAVLRRIQLQPTSIEKEVFPI
MAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKQPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDARIRSH
SWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM
 
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