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MGP005033

Record overview

MGPD IDMGP005033
Gene ID29968
SpeciesHomo sapiens (Human)
Gene Namephosphoserine aminotransferase 1
Gene Symbol PSAT1
SynonymsPSA; EPIP; NLS2; PSAT; PSATD;
Alternate namesphosphoserine aminotransferase; endometrial progesterone-induced protein; phosphohydroxythreonine aminotransferase;
Chromosome9
Map Location9q21.2
EC Number2.6.1.52
SummaryThis gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8. [provided by RefSeq, Jul 2013]
OrthologsView orthologs and multiple alignments for PSAT1

Proteins

phosphoserine aminotransferase isoform 1
Refseq ID:NP_478059
Protein GI:17402893
UniProt ID:Q9Y617
mRNA ID:NM_058179
Length:370
RefSeq Status:
MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGRCAD
YVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSNFLSKPVDVSKFGVIFAGAQK
NVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVCPVEPQNRSK
MNIPFRIGNAKGDDALEKRFLDKALELNMLSLKGHRSVGGIRASLYNAVTIEDVQKLAAFMKKFLEMHQL
 
phosphoserine aminotransferase isoform 2
Refseq ID:NP_066977
Protein GI:10863955
UniProt ID:Q9Y617
mRNA ID:NM_021154
Length:324
RefSeq Status:
MDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCGQFSAVPLNLIGLKAGRCAD
YVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSNFLSKPVDVSKFGVIFAGAQK
NVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQGFYVSVGGIRASLY
NAVTIEDVQKLAAFMKKFLEMHQL
 
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