MGP Database

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MGP005053

Ontology/Pathway Information

Entrez Gene ID50484
Gene Nameribonucleotide reductase M2 B (TP53 inducible)
Gene Symbol RRM2B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005654 IDA:HPACnucleoplasm
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004748 IEA:UniProtKB-ECFribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0009186 IEA:InterProPdeoxyribonucleoside diphosphate metabolic process
GO:0009200 IEA:EnsemblPdeoxyribonucleoside triphosphate metabolic process
GO:0009263 IEA:EnsemblPdeoxyribonucleotide biosynthetic process
GO:0006281 IEA:UniProtKB-KWPDNA repair
GO:0001822 IEA:EnsemblPkidney development
GO:0006264 IEA:EnsemblPmitochondrial DNA replication
GO:1902254 IEA:EnsemblPnegative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO:0015949 TAS:ReactomePnucleobase-containing small molecule interconversion
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0003014 IEA:EnsemblPrenal system process
GO:0006979 IEA:EnsemblPresponse to oxidative stress
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_21330Synthesis and interconversion of nucleotide di- and triphosphates
SMP Pathway Links
SMP IDDescription
SMP00172Beta Ureidopropionase Deficiency
SMP00178Dihydropyrimidinase Deficiency
SMP00446Gemcitabine Action Pathway
SMP00603Gemcitabine Metabolism Pathway
SMP00202MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
SMP00046Pyrimidine Metabolism
SMP00219UMP Synthase Deiciency (Orotic Aciduria)
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