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MGP005131

Record overview

MGPD IDMGP005131
Gene ID51144
SpeciesHomo sapiens (Human)
Gene Namehydroxysteroid (17-beta) dehydrogenase 12
Gene Symbol HSD17B12
SynonymsKAR; SDR12C1;
Alternate namesestradiol 17-beta-dehydrogenase 12; 17-beta-HSD 12; 17-beta-hydroxysteroid dehydrogenase 12; 17beta-HSD type 12; 3-ketoacyl-CoA reductase; short chain dehydrogenase/reductase family 12C, member 1; steroid dehydrogenase homolog;
Chromosome11
Map Location11p11.2
EC Number1.1.1.62
SummaryThis gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011]
OrthologsView orthologs and multiple alignments for HSD17B12

Proteins

estradiol 17-beta-dehydrogenase 12
Refseq ID:NP_057226
Protein GI:7705855
UniProt ID:Q53GQ0
mRNA ID:NM_016142
Length:312
RefSeq Status:
MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKV
ETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLT
IYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKS
TRAHYLKKTKKN
 
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