MGP Database

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MGP005176

Record overview

MGPD IDMGP005176
Gene ID51380
SpeciesHomo sapiens (Human)
Gene Namecysteine sulfinic acid decarboxylase
Gene Symbol CSAD
SynonymsCSD; PCAP;
Alternate namescysteine sulfinic acid decarboxylase; P-selectin cytoplasmic tail-associated protein; cysteine sulfinic acid decarboxylase-related protein; cysteine-sulfinate decarboxylase; sulfinoalanine decarboxylase;
Chromosome12
Map Location12q13.11-q14.3
SummaryThis gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
OrthologsView orthologs and multiple alignments for CSAD

Proteins

cysteine sulfinic acid decarboxylase isoform 1
Refseq ID:NP_057073
Protein GI:194294551
UniProt ID:Q9Y600
mRNA ID:NM_015989
Length:520
RefSeq Status:
MSIPLKSSFLLSYLCTLPPALLSREILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILER
CRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQ
RGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVD
AAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQG
DQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSA
LTCADMDFLLNELERLGQDL
 
cysteine sulfinic acid decarboxylase isoform 2
Refseq ID:NP_001231634
Protein GI:347659021
UniProt ID:Q86V02
mRNA ID:NM_001244705
Length:493
RefSeq Status:
MADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPH
ALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAF
LGLGTDSVRVVKADERGKMVPEDLERQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVA
WNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREG
FELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL
 
cysteine sulfinic acid decarboxylase isoform 3
Refseq ID:NP_001231635
Protein GI:347659023
UniProt ID:Q96JQ3
mRNA ID:NM_001244706
Length:260
RefSeq Status:
MGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQA
SYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHER
LSKVAPVLKERMVKEGSMMIGYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL
 
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