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MGP005253

UniProt Annotations

Entry Information
Gene Namecoenzyme Q3 methyltransferase
Protein EntryCOQ3_HUMAN
UniProt IDQ9NZJ6
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityS-adenosyl-L-methionine + 3,4-dihydroxy-5-all- trans-polyprenylbenzoate = S-adenosyl-L-homocysteine + 3-methoxy- 4-hydroxy-5-all-trans-polyprenylbenzoate. {ECO:0000269|PubMed:10777520}.
Catalytic ActivityS-adenosyl-L-methionine + 3-(all-trans- polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2- methoxy-6-(all-trans-polyprenyl)phenol. {ECO:0000269|PubMed:10777520}.
Catalytic ActivityS-adenosyl-L-methionine + 3- demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n. {ECO:0000269|PubMed:10777520}.
PathwayCofactor biosynthesis; ubiquinone biosynthesis.
Sequence CautionSequence=AAF66826.1; Type=Frameshift; Positions=16, 18, 22, 26, 44, 49, 60, 363, 364; Evidence={ECO:0000305};
SimilarityBelongs to the methyltransferase superfamily. UbiG/COQ3 family. {ECO:0000305}.
Subcellular LocationMitochondrion matrix {ECO:0000305}.
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