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MGP005263

Record overview

MGPD IDMGP005263
Gene ID53826
SpeciesHomo sapiens (Human)
Gene NameFXYD domain containing ion transport regulator 6
Gene Symbol FXYD6
Alternate namesFXYD domain-containing ion transport regulator 6; phosphohippolin;
Chromosome11
Map Location11q23.3
SummaryThis gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011]
OrthologsView orthologs and multiple alignments for FXYD6

Proteins

FXYD domain-containing ion transport regulator 6 precursor
Refseq ID:NP_071286
Protein GI:11612655
UniProt ID:Q9H0Q3
mRNA ID:NM_022003
Length:95
RefSeq Status:
MELVLVFLCSLLAPMVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
 
sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
 
FXYD domain-containing ion transport regulator 6 precursor
Refseq ID:NP_001158303
Protein GI:258679500
UniProt ID:Q9H0Q3
mRNA ID:NM_001164831
Length:95
RefSeq Status:
Protein sequence is identical to GI:11612655 (mRNA isoform)
 
sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
 
FXYD domain-containing ion transport regulator 6 precursor
Refseq ID:NP_001158309
Protein GI:258679520
UniProt ID:Q9H0Q3
mRNA ID:NM_001164837
Length:95
RefSeq Status:
Protein sequence is identical to GI:11612655 (mRNA isoform)
 
sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
 
FXYD domain-containing ion transport regulator 6 precursor
Refseq ID:NP_001158304
Protein GI:258679503
UniProt ID:Q9H0Q3
mRNA ID:NM_001164832
Length:95
RefSeq Status:
Protein sequence is identical to GI:11612655 (mRNA isoform)
 
sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
 
FXYD domain-containing ion transport regulator 6 precursor
Refseq ID:NP_001158308
Protein GI:258679518
UniProt ID:Q9H0Q3
mRNA ID:NM_001164836
Length:95
RefSeq Status:
Protein sequence is identical to GI:11612655 (mRNA isoform)
 
sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1963
peptide sequence: 
MELVLVFLCSLLAPMVLA

mat_peptide: 19..95
product: FXYD domain-containing ion transport regulator 6
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H0Q3.1)
calculated_mol_wt: 8598
peptide sequence: 
SAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRRCKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN
 
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