MGP Database

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MGP005275

Ontology/Pathway Information

Entrez Gene ID54205
Gene Namecytochrome c, somatic
Gene Symbol CYCS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IMP:UniProtKBCcytosol
GO:0005743 TAS:ReactomeCmitochondrial inner membrane
GO:0005758 TAS:UniProtKBCmitochondrial intermembrane space
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0005634 IDA:UniProtKBCnucleus
GO:0000159 TAS:UniProtKBCprotein phosphatase type 2A complex
GO:0070469 IEA:UniProtKB-KWCrespiratory chain
GO:0045155 IDA:UniProtKBFelectron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
GO:0020037 TAS:UniProtKBFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0008635 TAS:UniProtKBPactivation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0006309 IMP:UniProtKBPapoptotic DNA fragmentation
GO:0006915 TAS:ReactomePapoptotic process
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0045333 TAS:UniProtKBPcellular respiration
GO:0016311 TAS:GOCPdephosphorylation
GO:0097193 TAS:ReactomePintrinsic apoptotic signaling pathway
GO:0006123 IBA:GO_CentralPmitochondrial electron transport, cytochrome c to oxygen
GO:0006122 IBA:GO_CentralPmitochondrial electron transport, ubiquinol to cytochrome c
GO:0022904 TAS:ReactomePrespiratory electron transport chain
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_607Activation of caspases through apoptosome-mediated cleavage
REACT_578Apoptosis
REACT_963Apoptotic factor-mediated response
REACT_120956Cellular responses to stress
REACT_831Cytochrome c-mediated apoptotic response
REACT_264249Detoxification of Reactive Oxygen Species
REACT_89Formation of apoptosome
REACT_964Intrinsic Pathway for Apoptosis
REACT_111217Metabolism
REACT_264351Mitochondrial biogenesis
REACT_264135Organelle biogenesis and maintenance
REACT_268444Orphan transporters
REACT_268456Programmed Cell Death
REACT_1322Release of apoptotic factors from the mitochondria
REACT_22393Respiratory electron transport
REACT_6305Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
REACT_264212Transcriptional activation of mitochondrial biogenesis
REACT_15518Transmembrane transport of small molecules
SMP Pathway Links
SMP IDDescription
SMP00355Mitochondrial Electron Transport Chain
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