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MGP005280

Record overview

MGPD IDMGP005280
Gene ID54344
SpeciesHomo sapiens (Human)
Gene Namedolichyl-phosphate mannosyltransferase polypeptide 3
Gene Symbol DPM3
SynonymsCDG1O;
Alternate namesdolichol-phosphate mannosyltransferase subunit 3; DPM synthase complex subunit 3; DPM synthase subunit 3; MPD synthase subunit 3; dolichol-phosphate mannose synthase subunit 3; dolichyl-phosphate beta-D-mannosyltransferase subunit 3; mannose-P-dolichol synthase subunit 3; prostin 1; prostin-1;
Chromosome1
Map Location1q22
SummaryDolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for DPM3

Proteins

dolichol-phosphate mannosyltransferase subunit 3 isoform 1
Refseq ID:NP_061846
Protein GI:19424120
UniProt ID:Q9P2X0
mRNA ID:NM_018973
Length:122
RefSeq Status:
MLSVGGLRLSLVRFSFLLLRGALLPSLAVTMTKLAQWLWGLAILGSTWVALTTGALGLELPLSCQEVLWPLPAYLLVSAGCYALGTVGYRVATFHDCEDA
ARELQSQIQEARADLARRGLRF
 
dolichol-phosphate mannosyltransferase subunit 3 isoform 2
Refseq ID:NP_714963
Protein GI:24430135
UniProt ID:Q86TM7
mRNA ID:NM_153741
Length:92
RefSeq Status:
MTKLAQWLWGLAILGSTWVALTTGALGLELPLSCQEVLWPLPAYLLVSAGCYALGTVGYRVATFHDCEDAARELQSQIQEARADLARRGLRF
 
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