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MGP005382

UniProt Annotations

Entry Information
Gene NameHAUS augmin-like complex, subunit 2
Protein EntryHAUS2_HUMAN
UniProt IDQ9NVX0
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9NVX0-1; Sequence=Displayed; Name=2; IsoId=Q9NVX0-2; Sequence=VSP_012223; Name=3; IsoId=Q9NVX0-3; Sequence=VSP_040918; Note=No experimental confirmation available.;
FunctionContributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.
SimilarityBelongs to the HAUS2 family. {ECO:0000305}.
Subcellular LocationCytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.
SubunitComponent of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}.
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