MGP Database

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MGP005525

Ontology/Pathway Information

Entrez Gene ID55970
Gene Nameguanine nucleotide binding protein (G protein), gamma 12
Gene Symbol GNG12
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005884 IEA:EnsemblCactin filament
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005834 IEA:InterProCheterotrimeric G-protein complex
GO:0005886 TAS:ReactomeCplasma membrane
GO:0030165 IDA:MGIFPDZ domain binding
GO:0042301 IEA:EnsemblFphosphate ion binding
GO:0004871 IEA:UniProtKB-KWFsignal transducer activity
GO:0071377 TAS:ReactomePcellular response to glucagon stimulus
GO:0021987 IEA:EnsemblPcerebral cortex development
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0007186 IEA:InterProPG-protein coupled receptor signaling pathway
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0007165 TAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_25330Activation of GABAB receptors
REACT_75831Activation of G protein gated Potassium channels
REACT_21312Activation of Kainate Receptors upon glutamate binding
REACT_19140ADP signalling through P2Y purinoceptor 1
REACT_20653ADP signalling through P2Y purinoceptor 12
REACT_18339Adrenaline,noradrenaline inhibits insulin secretion
REACT_23887Aquaporin-mediated transport
REACT_264224beta-catenin independent WNT signaling
REACT_263982Ca2+ pathway
REACT_18372Class B/2 (Secretin family receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_25031GABA B receptor activation
REACT_25199GABA receptor activation
REACT_18407G alpha (12/13) signalling events
REACT_19231G alpha (i) signalling events
REACT_18283G alpha (q) signalling events
REACT_19327G alpha (s) signalling events
REACT_19333G alpha (z) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_19145G beta:gamma signalling through PLC beta
REACT_18274Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
REACT_1665Glucagon signaling in metabolic regulation
REACT_18377Glucagon-type ligand receptors
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_15457G-protein activation
REACT_19388G-protein beta:gamma signalling
REACT_75780G protein gated Potassium channels
REACT_604Hemostasis
REACT_25004Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
REACT_1505Integration of energy metabolism
REACT_75918Inwardly rectifying K+ channels
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_15295Opioid Signalling
REACT_798Platelet activation, signaling and aggregation
REACT_23876Platelet homeostasis
REACT_75908Potassium Channels
REACT_21254Presynaptic function of Kainate receptors
REACT_23946Prostacyclin signalling through prostacyclin receptor
REACT_18325Regulation of insulin secretion
REACT_20524Signal amplification
REACT_14797Signaling by GPCR
REACT_11045Signaling by Wnt
REACT_111102Signal Transduction
REACT_21384Thrombin signalling through proteinase activated receptors (PARs)
REACT_20647Thromboxane signalling through TP receptor
REACT_15518Transmembrane transport of small molecules
REACT_13477Transmission across Chemical Synapses
REACT_24023Vasopressin regulates renal water homeostasis via Aquaporins
SMP Pathway Links
SMP IDDescription
SMP00310Corticotropin Activation of Cortisol Production
SMP00308Dopamine Activation of Neurological Reward System
SMP00309Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
SMP00312Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
SMP00311Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
SMP00320Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
SMP00321Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
SMP00333Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone
SMP00335Intracellular Signalling Through Histamine H2 Receptor and Histamine
SMP00338Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin
SMP00343Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
SMP00354Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin
SMP00322Vasopressin Regulation of Water Homeostasis
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