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MGP005537

Record overview

MGPD IDMGP005537
Gene ID56267
SpeciesHomo sapiens (Human)
Gene Namecysteine conjugate-beta lyase 2
Gene Symbol CCBL2
SynonymsKAT3; KATIII;
Alternate nameskynurenine--oxoglutarate transaminase 3; RP11-82K18.3; cysteine-S-conjugate beta-lyase 2; kynurenine aminotransferase III; kynurenine--glyoxylate transaminase; kynurenine--oxoglutarate transaminase III; kynurenine-oxoglutarate transaminase 3;
Chromosome1
Map Location1p22.2
EC Number2.6.1.7
SummaryThis gene encodes an aminotransferase that transaminates kynurenine to form kynurenic acid. Kynurenic acid is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. This gene shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping. [provided by RefSeq, Jun 2009]
OrthologsView orthologs and multiple alignments for CCBL2

Proteins

kynurenine--oxoglutarate transaminase 3 isoform 1
Refseq ID:NP_001008661
Protein GI:56713254
UniProt ID:Q6YP21
mRNA ID:NM_001008661
Length:454
RefSeq Status:
MFLAQRSLCSLSGRAKFLKTISSSKILGFSTSAKMSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRG
FGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQEL
ESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIK
HLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKW
MTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS
 
kynurenine--oxoglutarate transaminase 3 isoform 2
Refseq ID:NP_001008662
Protein GI:56713256
UniProt ID:Q6YP21
mRNA ID:NM_001008662
Length:420
RefSeq Status:
MSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGA
YGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIAD
LCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDD
PECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIK
KDSTLDAAEEIIKAWSVQKS
 
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