MGP Database

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MGP005547

Ontology/Pathway Information

Entrez Gene ID56603
Gene Namecytochrome P450, family 26, subfamily B, polypeptide 1
Gene Symbol CYP26B1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0020037 NAS:BHF-UCLFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0008401 IDA:BHF-UCLFretinoic acid 4-hydroxylase activity
GO:0001972 IDA:BHF-UCLFretinoic acid binding
GO:0060349 IMP:UniProtKBPbone morphogenesis
GO:0001709 ISS:BHF-UCLPcell fate determination
GO:0071300 IEA:EnsemblPcellular response to retinoic acid
GO:0070268 IEA:EnsemblPcornification
GO:0030326 ISS:BHF-UCLPembryonic limb morphogenesis
GO:0061436 IEA:EnsemblPestablishment of skin barrier
GO:0007140 ISS:BHF-UCLPmale meiosis
GO:0048387 TAS:BHF-UCLPnegative regulation of retinoic acid receptor signaling pathway
GO:0055114 IDA:BHF-UCLPoxidation-reduction process
GO:0010628 IEA:EnsemblPpositive regulation of gene expression
GO:2001037 IEA:EnsemblPpositive regulation of tongue muscle cell differentiation
GO:0009954 ISS:BHF-UCLPproximal/distal pattern formation
GO:0034653 IDA:BHF-UCLPretinoic acid catabolic process
GO:0048384 IEA:EnsemblPretinoic acid receptor signaling pathway
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007283 ISS:BHF-UCLPspermatogenesis
GO:0043587 IEA:EnsemblPtongue morphogenesis
GO:0006766 TAS:ReactomePvitamin metabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13433Biological oxidations
REACT_13567Cytochrome P450 - arranged by substrate type
REACT_268767Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
REACT_268601Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4)
REACT_268761Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency)
REACT_268217Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5)
REACT_268478Defective CYP19A1 causes Aromatase excess syndrome (AEXS)
REACT_268087Defective CYP1B1 causes Glaucoma
REACT_267893Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3)
REACT_268803Defective CYP24A1 causes Hypercalcemia, infantile (HCAI)
REACT_268108Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)
REACT_267734Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4)
REACT_268413Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX)
REACT_268633Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A)
REACT_268491Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B)
REACT_268326Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56)
REACT_268441Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
REACT_267709Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3)
REACT_268486Defective FMO3 causes Trimethylaminuria (TMAU)
REACT_267863Defective MAOA causes Brunner syndrome (BRUNS)
REACT_268528Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)
REACT_116125Disease
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_13705Phase 1 - Functionalization of compounds
REACT_268561RA biosynthesis pathway
REACT_267785Signaling by Retinoic Acid
REACT_111102Signal Transduction
REACT_13450Vitamins
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