MGP Database

MGP005564

UniProt Annotations

Entry Information
Gene Namedihydropyrimidinase-like 5
Protein EntryDPYL5_HUMAN
UniProt IDQ9BPU6
SpeciesHuman
Comments
Comment typeDescription
CautionLacks most of the conserved residues that are essential for binding the metal cofactor and hence for dihydropyrimidinase activity. Its enzyme activity is therefore unsure. {ECO:0000305}.
FunctionMay have a function in neuronal differentiation and/or axon growth.
SimilarityBelongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000305}.
SubunitHomotetramer, and heterotetramer with other DPYS-like proteins. Interacts with DPYSL2, DPYSL3 and DPYSL4 (By similarity). {ECO:0000250}.
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