MGP Database

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MGP005699

Ontology/Pathway Information

Entrez Gene ID59272
Gene Nameangiotensin I converting enzyme 2
Gene Symbol ACE2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0005737 IEA:UniProtKB-SubCellCcytoplasm
GO:0005576 IDA:UniProtKBCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0045121 TAS:BHF-UCLCmembrane raft
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0004180 IDA:UniProtKBFcarboxypeptidase activity
GO:0004175 IDA:UniProtKBFendopeptidase activity
GO:0001948 IPI:BHF-UCLFglycoprotein binding
GO:0017046 IEA:EnsemblFpeptide hormone binding
GO:0001618 IMP:UniProtKBFvirus receptor activity
GO:0008270 TAS:BHF-UCLFzinc ion binding
GO:0002005 IC:BHF-UCLPangiotensin catabolic process in blood
GO:0002003 TAS:ReactomePangiotensin maturation
GO:0003051 IMP:BHF-UCLPangiotensin-mediated drinking behavior
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0060135 IEA:EnsemblPmaternal process involved in female pregnancy
GO:2000379 IC:BHF-UCLPpositive regulation of reactive oxygen species metabolic process
GO:0032800 IMP:BHF-UCLPreceptor biosynthetic process
GO:0046813 IDA:BHF-UCLPreceptor-mediated virion attachment to host cell
GO:0042127 TAS:BHF-UCLPregulation of cell proliferation
GO:0001817 IC:BHF-UCLPregulation of cytokine production
GO:0050727 IC:BHF-UCLPregulation of inflammatory response
GO:0003081 IMP:BHF-UCLPregulation of systemic arterial blood pressure by renin-angiotensin
GO:0019229 IC:BHF-UCLPregulation of vasoconstriction
GO:0042312 IC:BHF-UCLPregulation of vasodilation
GO:0009615 IDA:GOCPresponse to virus
GO:0046718 TAS:UniProtKBPviral entry into host cell
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_147707Metabolism of Angiotensinogen to Angiotensins
REACT_17015Metabolism of proteins
REACT_160078Peptide hormone metabolism
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