MGP Database

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MGP005720

UniProt Annotations

Entry Information
Gene Namesignal peptidase complex subunit 3 homolog (S. cerevisiae)
Protein EntrySPCS3_HUMAN
UniProt IDP61009
SpeciesHuman
Comments
Comment typeDescription
FunctionComponent of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
SimilarityBelongs to the SPCS3 family. {ECO:0000305}.
Subcellular LocationMicrosome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
SubunitComponent of the microsomal signal peptidase complex which consists of five members: SEC11A, SEC11C, SPCS1, SPCS2 and SPCS3. {ECO:0000250}.
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