MGP Database

MGP005752

Ontology/Pathway Information

Entrez Gene ID	64170
Gene Name	caspase recruitment domain family, member 9
Gene Symbol	CARD9
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0050700	IPI:UniProtKB	F	CARD domain binding
GO:0042803	IPI:UniProtKB	F	protein homodimerization activity
GO:0050830	IEA:Ensembl	P	defense response to Gram-positive bacterium
GO:0051607	IEA:Ensembl	P	defense response to virus
GO:0045087	TAS:Reactome	P	innate immune response
GO:0035872	TAS:Reactome	P	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0070423	TAS:Reactome	P	nucleotide-binding oligomerization domain containing signaling pathway
GO:0043123	IEP:UniProtKB	P	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755	IEA:Ensembl	P	positive regulation of interleukin-6 production
GO:0046330	IDA:MGI	P	positive regulation of JNK cascade
GO:0032874	IDA:MGI	P	positive regulation of stress-activated MAPK cascade
GO:0032760	IEA:Ensembl	P	positive regulation of tumor necrosis factor production
GO:0042981	IEA:InterPro	P	regulation of apoptotic process
GO:0045076	IEA:Ensembl	P	regulation of interleukin-2 biosynthetic process
GO:0045408	IEA:Ensembl	P	regulation of interleukin-6 biosynthetic process
GO:0042534	IEA:Ensembl	P	regulation of tumor necrosis factor biosynthetic process
GO:0042493	IEA:Ensembl	P	response to drug
GO:0043330	IEA:Ensembl	P	response to exogenous dsRNA
GO:0009620	IEA:Ensembl	P	response to fungus
GO:0032495	IEA:Ensembl	P	response to muramyl dipeptide
GO:0032494	IEA:Ensembl	P	response to peptidoglycan

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_6900	Immune System
REACT_6802	Innate Immune System
REACT_75776	NOD1/2 Signaling Pathway
REACT_75913	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways