MGP Database

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MGP005842

Ontology/Pathway Information

Entrez Gene ID79001
Gene Namevitamin K epoxide reductase complex, subunit 1
Gene Symbol VKORC1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0048038 IEA:UniProtKB-KWFquinone binding
GO:0047057 IDA:UniProtKBFvitamin-K-epoxide reductase (warfarin-sensitive) activity
GO:0007596 IMP:UniProtKBPblood coagulation
GO:0060348 ISS:UniProtKBPbone development
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0017144 IMP:UniProtKBPdrug metabolic process
GO:0017187 IMP:UniProtKBPpeptidyl-glutamic acid carboxylation
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0042373 IDA:UniProtKBPvitamin K metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1069Gamma carboxylation, hypusine formation and arylsulfatase activation
REACT_1132Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
SMP Pathway Links
SMP IDDescription
SMP00269Acenocoumarol Action Pathway
SMP00280Alteplase Action Pathway
SMP00286Aminocaproic Acid Action Pathway
SMP00281Anistreplase Action Pathway
SMP00288Aprotinin Action Pathway
SMP00275Ardeparin Action Pathway
SMP00276Argatroban Action Pathway
SMP00277Bivalirudin Action Pathway
SMP00586Coagulation
SMP00656Dicoumarol Action Pathway
SMP00270Dicumarol Action Pathway
SMP00272Enoxaparin Action Pathway
SMP00273Fondaparinux Action Pathway
SMP00274Heparin Action Pathway
SMP00278Lepirudin Action Pathway
SMP00655Phenindione Action Pathway
SMP00271Phenprocoumon Action Pathway
SMP00285Reteplase Action Pathway
SMP00282Streptokinase Action Pathway
SMP00283Tenecteplase Action Pathway
SMP00287Tranexamic Acid Action Pathway
SMP00284Urokinase Action Pathway
SMP00464Vitamin K Metabolism
SMP00268Warfarin Action Pathway
SMP00279Ximelagatran Action Pathway
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