MGP Database

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MGP005851

UniProt Annotations

Entry Information
Gene NameELOVL fatty acid elongase 6
Protein EntryELOV6_HUMAN
UniProt IDQ9H5J4
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
FunctionCondensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16:0 acyl-CoAs. {ECO:0000269|PubMed:20937905}.
PtmN-Glycosylated. {ECO:0000269|PubMed:20937905}.
Sequence CautionSequence=BAC11225.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the ELO family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000269|PubMed:20937905}.
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:20937905}.
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