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MGP005897

Record overview

MGPD IDMGP005897
Gene ID79682
SpeciesHomo sapiens (Human)
Gene Namecentromere protein U
Gene Symbol CENPU
SynonymsKLIP1; PBIP1; CENP50; MLF1IP; CENPU50;
Alternate namescentromere protein U; KSHV latent nuclear antigen interacting protein 1; KSHV latent nuclear antigen-interacting protein 1; MLF1 interacting protein; MLF1-interacting protein; centromere protein of 50 kDa; interphase centromere complex protein 24; polo-box-interacting protein 1;
Chromosome4
Map Location4q35.1
SummaryThe centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for CENPU

Proteins

centromere protein U
Refseq ID:NP_078905
Protein GI:38016935
UniProt ID:Q71F23
mRNA ID:NM_024629
Length:418
RefSeq Status:
MAPRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKCKPIDVFDFPDNSDVSSIGRLGENEKDEETYETFDPPLHSTAIYADEEEFSKHCGLSLSSTPP
GKEAKRSSDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRTTASSELSEKPAESVTSKKTGPLSAQPSVEKENL
AIESQSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIWCPEGMKTSDIKELNIVLPEFEKTHLEHQQRIESKVCKAAIATFYVNVKEQFIKMLKESQMLT
NLKRKNAKMISDIEKKRQRMIEVQDELLRLEPQLKQLQTKYDELKERKSSLRNAAYFLSNLKQLYQDYSDVQAQEPNVKETYDSSSLPALLFKARTLLGA
ESHLRNINHQLEKLLDQG
 
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