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MGP005934

Record overview

MGPD IDMGP005934
Gene ID79888
SpeciesHomo sapiens (Human)
Gene Namelysophosphatidylcholine acyltransferase 1
Gene Symbol LPCAT1
SynonymsAYTL2; lpcat; PFAAP3;
Alternate nameslysophosphatidylcholine acyltransferase 1; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; LPC acyltransferase 1; LPCAT-1; acetyl-CoA:lyso-PAF acetyltransferase; acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyl-CoA:lysophosphatidylcholine acyltransferase 1; acyltransferase like 2; acyltransferase-like 2; lyso-PAF acetyltransferase; lysoPAFAT; lysoPC acyltransferase 1; phosphonoformate immuno-associated protein 3; regulated by phosphonoformate;
Chromosome5
Map Location5p15.33
EC Number2.3.1.23
SummaryLysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006 [PubMed 16704971]).[supplied by OMIM, May 2008]
OrthologsView orthologs and multiple alignments for LPCAT1

Proteins

lysophosphatidylcholine acyltransferase 1
Refseq ID:NP_079106
Protein GI:33946291
UniProt ID:Q8NF37
mRNA ID:NM_024830
Length:534
RefSeq Status:
MRLRGCGPRAAPASSAGASDARLLAPPGRNPFVHELRLSALQKAQVALMTLTLFPVRLLVAAAMMLLAWPLALVASLGSAEKEPEQPPALWRKVVDFLLK
AIMRTMWFAGGFHRVAVKGRQALPTEAAILTLAPHSSYFDAIPVTMTMSSIVMKAESRDIPIWGTLIQYIRPVFVSRSDQDSRRKTVEEIKRRAQSNGKW
PQIMIFPEGTCTNRTCLITFKPGAFIPGAPVQPVVLRYPNKLDTITWTWQGPGALEILWLTLCQFHNQVEIEFLPVYSPSEEEKRNPALYASNVRRVMAE
ALGVSVTDYTFEDCQLALAEGQLRLPADTCLLEFARLVRGLGLKPEKLEKDLDRYSERARMKGGEKIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVD
LRECVVALSVVCRPARTLDTIQLAFKMYGAQEDGSVGEGDLSCILKTALGVAELTVTDLFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHFES
CAETSPAPIPNGFCADFSPENSDAGRKPVRKKLD
 
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